Fetomaternal Alloimmune Thrombocytopenia (FMAIT)

• This project commenced in October 2006
• FMAIT is the most common cause of severe neonatal thrombocytopnia in otherwise well term infants, and can lead to serious bleeding, intracranial haemorrhage and sometimes death of the fetus or infant.
• First pregnancies are often severely affected and the diagnosis is usually made with the birth of a first afected infant.
• There is therefore a current debate about the utility of antenatal screening for the condition.
• The study aims to determine the true incidence of severe haemorrhage associated with FMAIT, to describe the clinical outcome of affected cases and to identify prognostic factors, and thus to inform ongoing review of the case for antenatal screening for this condition.
• Funded: Wellbeing of Women
• Ethics: The study has approval from the London Multicentre Research Ethics Committee (06/MRE02/53) and PIAG.
• Lead Investigator Dr Marian Knight,

For more information on this project visit the navigation bar.

Dr Marian Knight